Document Details
Document Type |
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Article In Journal |
Document Title |
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A CORRELATION STUDY OF SECRETORY IMMUNOGLOBULINS (s.IgA) LEVEL AND CARIOGENIC BACTERIA IN CHILDREN WITH SECC AND CARIES FREE CHILDREN AND THEIR CORRESPONDING MOTHERS A CORRELATION STUDY OF SECRETORY IMMUNOGLOBULINS (s.IgA) LEVEL AND CARIOGENIC BACTERIA IN CHILDREN WITH SECC AND CARIES FREE CHILDREN AND THEIR CORRESPONDING MOTHERS |
Document Language |
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English |
Abstract |
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Early childhood caries (ECC) is recognized as an infectious disease. The first step in its development
is primary infection by the bacterium S. mutans which has been identified as the
primary etiologic factors in dental caries. Lcictobacilli were also found to play a role in the
progression of disease. However, the underlying mechanism of immune response to caries is
unclear. The associa- tion between secretory IgA (s.IgA) and cariogenic microorganisms is still
controversial.
The aim of this study was to correlate the level of cariogenic bacteria and salivary IgA in caries
free children, and children with SECC and their corresponding mothers.
Sixty children and their mothers attending the dental clinic in King Abdulaziz University participated
in our study. Their age ranged from 3 - 5 years. The study groups consisted of thirty children
with SECC and a control group consisting of thirty caries free children.
Children together with their mothers were examined and their caries level was recorded. Stimulated
saliva was collected from each participant for bacterial and immunological assessment. S.
mutans and Lactobacilli counts in each sample were determined, using the Dento cult method and
the secretory IgA (s. IgA) level was assessed by ELISA test.
A significant correlation has been shown between mothers and children with SECC with respects
to salivary 5. mutans. A positive high correlation was found between s. IgA of mothers and
children in both groups |
ISSN |
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1 |
Journal Name |
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Egyptian Dental Journal |
Volume |
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52 |
Issue Number |
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2 |
Publishing Year |
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2006 AH
2006 AD |
Article Type |
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Article |
Added Date |
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Saturday, June 21, 2008 |
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Researchers
نجلاء العمودي | Al Amoudi, Najlaa | Investigator | Doctorate | nalamoudi@kau.edu.sa |
عزه هنو | Hanno, Azza | Researcher | Doctorate | Ahanno@kau.edu.sa |
عبدالله ال مشيط | Al Mushayt, Abdullah | Researcher | Doctorate | aalmushayt@kau.edu.sa |
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